Problems of Forensic Sciences 2012 Vol. 92 (XCII) 265-271
FREQUENCY ASSESSMENT OF 19 SNPs IN A POPULATION FROM SOUTH-WEST POLAND
Iwona CHROMIK, Małgorzata MAŁODOBRA, Tadeusz DOBOSZ
Department of Forensic Medicine, Molecular Technique Unit, Medical University of Wrocław, Poland
Streszczenie
This study presents the allele frequency distribution of 19 autosomal single nucleotide polymorphisms (SNPs). Allele and genotype frequencies of previously selected markers were assessed in 100 unrelated individuals originating from South-West Poland. No deviations from Hardy-Weinberg equilibrium (HWE) were revealed at any of the investigated loci within the analyzed population. All forensically relevant statistical parameters (i.e. Heto, Hetexp, PD, PE, PIC, PDtotal, PEtotal) were estimated as well. Finally, the results confirmed that these 19 loci are useful markers for forensic identification analysis.
Słowa kluczowe
Single nucleotide polymorphism; SNP; Human identification; Forensic genetics; SNP genotyping.