Problems of Forensic Sciences 2009 Vol. 77 (LXXVII) 89-97
DISTRIBUTION OF CHROMOSOME X STR MARKERS DXS10135, DXS10074, DXS10101 AND DXS10134 AND THEIR USEFULNESS IN FORENSIC GENETICS
Maciej JĘDRZEJCZYK, Renata JACEWICZ, Jarosław BERENT
Department of Legal Medicine, Medical University, Łódź, Poland
Streszczenie
This study focuses on the frequencies of four additional loci to the “core loci” included in the Mentype Argus X-8 PCR Amplification Kit (Biotype AG) and on haplotype frequencies determined in a Polish population sample. Forensic efficiency parameters of investigated loci were calculated. Deviations from HWE were not detected. For practical reasons, eight X-STR loci were coupled in four linkage groups (DXS8378-DXS10135, DXS7132-DXS10074, HPRTB-DXS10101 and DXS7423–DXS10134), established over the human X-chromosome. The Argus X-8 Amplification Kit was found to be an effective multiplex system and a useful addition to other markers routinely used in forensic practice, especially in difficult cases in kinship analyses.
Słowa kluczowe
Forensic genetics; X-chromosome; STRs; Central Poland.