Problems of Forensic Sciences 2009 Vol. 77 (LXXVII) 98-107
VARIATION OF 25 SNP POLYMORPHISMS IN THE LOWER SILESIAN POPULATION (SOUTH-WEST POLAND)
Iwona CHROMIK1, Małgorzata MAŁODOBRA1, Arleta LEBIODA1, Anna JONKISZ1, Magdalena ŻOŁĘDZIEWSKA1, Robert ŚMIGIEL2, Barbara TURCZYN3, Tadeusz ŁUKIEŃCZUK4, Małgorzata Radwan-OCZKO5, Edyta PAWLAK6, Anna SADAKIERSKA-CHUDY1, Marcelina ŻABIŃSKA1
1Department of Forensic Medicine, Medical Academy, Wrocław, Poland
2Department of Genetics, Medical Academy, Wrocław, Poland
3Department of Internal Medicine, Medical Academy, Wrocław, Poland
4Division of Clinical Procedures, Medical Academy, Wrocław, Poland
5Department of Periodontology, Medical Academy, Wrocław, Poland
6Department of Hematology, Medical Academy, Wrocław, Poland
Streszczenie
The most frequent type of human genetic variation – SNP (single nucleotide polymorphism) represents 90% of all alterations in the human genome. Genomic variability is responsible for the diversity observed in the human species. In the presented study, the frequencies of 25 SNPs were estimated from the Lower Silesian Population. Three of them showed high heterozygosity and might serve as future relevant identification markers, in spite of their medical connotations.
Słowa kluczowe
Forensic genetics; Genetic identification; Single nucleotide polymorphism (SNP); SNP genotyping.