ANALYSIS OF VOLATILE ORGANIC COMPOUNDS IN BLOOD OF PEOPLE CONSUMING ALCOHOLIC DRINKS BY MEANS OF GAS CHROMATOGRAPHY

Problems of Forensic Sciences 1998 Vol. 38 (XXXVIII) 36-54

ANALYSIS OF VOLATILE ORGANIC COMPOUNDS IN BLOOD OF PEOPLE CONSUMING ALCOHOLIC DRINKS BY MEANS OF GAS CHROMATOGRAPHY

Dariusz ZUBA¹, Zofia CHŁOBOWSKA², Andrzej PARCZEWSKI¹
¹Faculty of Chemistry, Jagiellonian University, Cracow
²Institute of Forensic Research, Cracow

Streszczenie
An attempt to work out a method for analysis of acetone, ethanal, ethanol, methanol, 1-propanol and 2-propanol in blood was described in the presented publication. The analysis was performed using the head-space technique after salting out the determined compounds by use of saturated solution of potassium carbonate. The main analytical parameters of the method were shown. The specific features of the method are a good precision (maximal relative standard deviation for samples of different concentration ranges did not exceed 8%), and a good accuracy (for most of the standard solution s the relative systematic error included in the range 1-3%). The technique was applied successfully to analyse blood samples taken from alcohol addicted persons as well as to study the kinetics of absorption of volatile compounds in blood after a consumption of alcohol.

Słowa kluczowe
Volatile compounds in blood; Ethanol; Methanol; Acetone; 1-propanol; 2-propanol; Gas chromatography; Salting out.