Problems of Forensic Sciences 2000 Vol. 43 (XLIII) 164-170
METHADONE SUBSTITUTION THERAPY PROGRAM AND TOXICOLOGICAL STUDIES
Halina MATSUMOTO, Elżbieta WOŹNY, Anna DZIKLIŃSKA, Małgorzata ABRAMOWSKA
Laboratory of Psychopharmacology, 1st Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland
Streszczenie
Methadone Substitution Therapy Program for opiate addicts at Nowowiejski Hospital in Warsaw lasted 6 years. During that time, 11424 drug of abuse analyses in urine probes were carried out by FPIA method on TDx Abbott analyser, to assess objectively methadone treatment efficacy. The results of toxicological studies indicate to a decrease of positive results (24–34% according to the drug in 1993 and 2.4–7.4% in 1997) in the first 5 years of the execution of the Program. But in the last year of the studies (1998) more opiates (9%), amphetamines (7.8%) and barbiturates (4.6%) were detected in urine of the patients.
Słowa kluczowe
Methadone; Drug of abuse; Opiates; Amphetamine.