Problems of Forensic Sciences 2000 Vol. 43 (XLIII) 208-216
ANALYSIS OF ESTAZOLAM IN POST-MORTEM MATERIAL
Ewa PUFAL1, Marzena SYKUTERA1, Grzegorz LIS1, Gertrud ROCHHOLZ2, Karol ŚLIWKA1
1Chair and Department of Forensic Medicine, Medical Academy, Bydgoszcz, Poland
2Institut für Rechtsmedizin, Kiel, Germany
Streszczenie
In this study, an evaluation of suitable extraction and clean up techniques for Estazolam in whole blood and organ material was done. Solvent extraction methods were compared with solid-phase extraction using Extrelut® or modified silica adsorbents. For end-step detection method TLC, UV-spectrophotometry, high pressure liquid chromatography (HPLC) with UV detector and gas chromatography-mass spectrometry (GC/MSD) were evaluated.
Słowa kluczowe
Estazolam; Post-mortem material; Solid-phase extraction; GC/MS.