Problems of Forensic Sciences 2000 Vol. 43 (XLIII) 283-289
DISTRIBUTION OF HEAVY METALS IN NORMAL KOREAN TISSUES
Youngchan YOO1, Sangki LEE1, Jayeol YANG1, Sangwhan IN1, Kiuk KIM1, Sunchun KIM1, Taejung KWON1, Youngchang KO1, Kyuhyuck CHUNG2
1National Institute of Scientific Investigation, Seoul, Korea
2College of Pharmacy, Sungkyunkwan University, Suwon, Korea
Streszczenie
To obtain the usual value of arsenic, cadmium, chromium, copper, iron, lead, manganese, mercury, molybdenum, nickel, selenium, silicon, tin, vanadium and zinc in the normal human body, the amounts of 15 metals were determined in 61 male and 30 female Korean cadavers, whose ages ranged from 12 to 87 years. Inductively coupled plasma atomic emission spectrometry was used for analysis of heavy metals in 10 autopsied human organs (liver, kidney, cerebrum, heart, spleen, lung, bone, blood, hair and nail). Distribution of arsenic, nickel, selenium, tin and vanadium in human body were almost uniform. Cadmium, mercury, manganese, molybdenum, lead and zinc were found in large quantities in the metabolic organs, whereas concentration of chromium and silicon were greatest in the tissues exposed to the exterior. Positive correlation with age was observed in the following cases: Cd in liver, kidney and cerebrum; Fe in cerebrum and bone; Pb in bone; Si in lung and bone; V in lung. Copper in heart, Hg in bone and Mn in kidney correlated negatively with age. A significantly positive correlation between Se and Hg was only observed in heart. Significant correlation coefficients between Se and As were observed in liver, kidney, heart, spleen and bone. The correlation between Cd and Zn was significant in liver and kidney, indicating that the distribution of Cd is similar to that of Zn in the liver and kidney.
Słowa kluczowe
Heavy metals; Human tissues; ICP-AES.