Problems of Forensic Sciences 2000 Vol. 42 (XLII) 122-129
SELECTIVITY OF PHOTODIODE ARRAY UV SPECTRA FOR SUBSTANCE IDENTIFICATION IN SYSTEMATIC TOXICOLOGICAL ANALYSIS
Matthias HERZLER, Fritz PRAGST, Sieglinde HERRE, Michael ROTHE
Institute of Legal Medicine, Department of Toxicological Chemistry, Humbolt University, Berlin, Germany
Streszczenie
An attempt was made to evaluate the selectivity of PDA UV spectra for systematic toxicological analysis (STA). A great spectral variety was found among compounds of toxicological interest. With modern generation PDA detectors even compounds of high structural similarity can be successfully distinguished down to a LOI as low as 10 ng/ml.
Słowa kluczowe
HPLC-photodiode array detection; UV spectra of toxic compounds; Systematic toxicological analysis.