Problems of Forensic Sciences 2000 Vol. 42 (XLII) 169-172
SCREENING FOR THE GENERAL UNKNOWN IN TISSUE SAMPLES BY POLYSTYRENE RESINS
Thomas STIMPFL, Walter VYCUDILIK
Institute of Forensic Medicine, University of Vienna, Vienna, Austria
Streszczenie
Screening for a broad range of different compounds in complex biological matrices needs a non-selective clean-up procedure. To meet this challenge, a semi-automatic method, appropriate to handle 5 ml of post-mortem blood or 1 g of tissue sample, using the polystyrene resins OASIS(tm) (Waters) or ISOLUTE(tm) 101 (IST) was developed. This procedure enables the isolation of lipophilic organic compounds from post-mortem tissue samples and is suitable for the toxicological screening of general unknown poisons in target organs.
Słowa kluczowe
Drug screening; Post-mortem material; Polystyrene resin.