Problems of Forensic Sciences 2000 Vol. 43 (XLIII) 222-230
BENZODIAZEPINE FINDINGS IN BLOOD AND URINE BY GAS CHROMATOGRAPHY AND IMMUNOASSAY
Ilpo RASANEN, Mikko NEUVONEN, Ilkka OJANPERÄ, Erkki VUORI
Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
Streszczenie
Gas chromatography (GC) and immunoassay techniques applied to blood and urine specimens were compared for the screening of benzodiazepines in post-mortem forensic toxicology. Five hundred and six such successive medical examiner’s cases were selected, where both urine and blood samples were available. Urine specimens were analysed by Emit® d.a.u.™ Benzodiazepine Assay. Blood and urine samples were screened for benzodiazepine drugs and their metabolites by an automated dual-column GC method. The results suggest that the present GC method for the blood seems to be a good alternative to the common combination of urine immunoassay followed by quantitative analysis of blood by chromatography.
Słowa kluczowe
Benzodiazepines; Immunoassay; Gas chromatography.