Problems of Forensic Sciences 2001 Vol. 48 (XLVIII) 31-52
CAPILLARY ELECTROPHORESIS AS A NEW TOOL IN FORENSIC TOXICOLOGICAL ANALYSIS
Katarzyna MADEJ
Faculty of Chemistry, Jagiellonian University, Cracow
Streszczenie
The basic aspects of capillary electrophoresis (CE) such as: instrumentation, separation modes and its chief domains of use in forensic analysis are presented. Micellar electrokinetic capillary chromatography (MECC), capillary zone electrophoresis (CZE) and chiral separations – the most often used separation modes in drugs analysis – are described. The main directions of development of CE methods in the field of forensic toxicological analysis are described. They are: 1. examination of abused drugs and accompanying compounds in confiscated illegal preparations, 2. analysis of abused drugs in biological samples and 3. determination of other drugs in biological and non-biological material. On the basis of a review of chemical and toxicological literature up to 2000, a variety of examples of CE applications to forensic drugs analysis is given.
Słowa kluczowe
Capillary electrophoresis; Forensic toxicology; Drugs; Biological and non-biological samples.