Problems of Forensic Sciences 2003 Vol. 56 (LVI) 17-25
ANALYSIS OF PROMAZINE IN BIOLOGICAL FLUIDS BY HPLC AND MECC WITH SPECTROPHOTOMETRIC DETECTION IN TWO CASES OF FATAL POISONING
Katarzyna MADEJ1, Maria KAŁA2, Michał WOŹNIAKIEWICZ1
1Faculty of Chemistry, Jagiellonian University, Cracow
2Institute of Forensic Research, Cracow
Streszczenie
Results of quantitative analyses of promazine in biological fluids (blood and urine) by high performance liquid chromatography (HPLC) and micellar electrokinetic capillary chromatography (MECC) were compared. Spectrophotometric detection was used for both methods. The examined samples originated from two forensic cases of fatal poisoning with promazine. The obtained results were presented and summarised. The basic validation parameters of the two applied methods were determined and compared.
Słowa kluczowe
Promazine; High performance liquid chromatography; Micellar electrokinetic capillary chromatography; Biological fluids.