Problems of Forensic Sciences 2018 Vol. 113 (CXIII) 5-26
THE INFLUENCE OF SELECTED BIOLOGICAL FACTORS ON THE INTERPRETATION OF DNA PROFILES (IN STR POLYMORPHIC SYSTEMS) IN THE PROCESS OF FORENSIC IDENTIFICATION
Ireneusz SOŁTYSZEWSKI1, Wojciech ACHREM2
1University of Warmia and Mazury in Olsztyn, Department of Criminalistics and Forensic Medicine, Olsztyn, Poland
2Criminalistics Laboratory, Voivodeship Police Headquarters in Szczecin, Szczecin, Poland
Streszczenie
The paradigm accepted in the process of identification (both positive and negative) in forensic genetic research is the stability of the system of genetic polymorphism regardless of the type of biological substance collected. However, forensic expert practice indicates that there are situations in which donors of such material have modified DNA profiles (due to various factors). Accordingly, a comparison of the DNA profiles of evidence and reference material can lead to significant interpretative problems, and in extreme cases this may lead to an erroneous outcome of the identification process. The purpose of this article is to summarize current knowledge about possible DNA modifications that are important for the identification process.
Słowa kluczowe
Individual identification; DNA analysis; Mutational variability; DNA profile modification; Chimerism; Uniparental disomy.