Problems of Forensic Sciences 2019 Vol. 117 (CXVII) 49-61
ANALYSIS OF THE FREQUENCY OF OCCURRENCE IN THE POLISH POPULATION OF ALLELES OF 21 GENETIC MARKERS IN THE GLOBALFILER KIT
Maria WRÓBEL, Agnieszka PARYS-PROSZEK, Magdalena MARCIŃSKA, Grażyna BA, Andrzej SEKUŁA, Marek KOWALCZYK, Miłosz JANUŁA, Andrzej DONIEC, Tomasz KUPIEC
Institute of Forensic Research, Kraków, Poland
Streszczenie
The purpose of this paper was to calculate allele frequencies of markers which are included in the GlobalFiler kit (ThermoFisher) for the Polish population. DNA quantification was carried out followed by PCR amplification and capillary electrophoresis of a set of 164 samples originating from non-related Polish individuals. Statistical analysis was conducted with GenoProof 3 (Qualitype).
The set of samples proved to be a good representation for the Polish population. Statistical analysis showed that parameters are acceptable. Allele frequencies were calculated for all of the autosomal markers. Implications: the database can be used for standard calculations in forensic genetics to estimate the power of evidence.
Słowa kluczowe
Population study; GlobalFiler; Kinship; Biostatistics.